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- MEDICINE, Page 61Snuffed SnifflesIs a cold remedy in sight?
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- Finding a cure for the common cold has been an elusive goal
- for generations. The reason: there are more than 100 different
- types of rhinoviruses, the culprits responsible for about half of
- all colds. Now scientists may have the key to warding off the
- sniffles. Reporting in the journal Cell last week, two separate
- research teams announced the discovery of a cell molecule to which
- rhinoviruses attach themselves. When the cold viruses bind to the
- molecule, known as the ICAM-1 receptor, they infect the cell.
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- The discovery means that synthetic copies of the molecule might
- one day be made into a decoy medicine. Sprayed into the nose, the
- drug could confuse invading rhinoviruses, luring them away from the
- real cell receptors in the body. Once bound to the synthetic, the
- viruses could be neutralized and thus prevented from causing colds.
- But that strategy, which might prevent but probably would not cure
- an active cold, has thus far worked only in the test tube. Relief
- is still years away.